Sunday, June 23, 2013

Louisiana man, 36, accused of killing teen rapper

WINNFIELD, La. (AP) ? Police in north Louisiana say a 36-year-old man is accused of killing the 18-year-old rapper known as Lil Snupe in an argument that broke out during a video game at a friend's apartment.

A news release says Winnfield police got a warrant Friday to arrest Tony Holden of Winnfield in the death of the rapper, whose actual name is Addarren Ross of Jonesboro.

Ross died Thursday morning at an apartment in Winnfield. He had been shot twice in the chest.

Holden could not be reached Friday. The phone at the only listing under that name was not answered.

Ross had recently signed a recording deal with the Meek Mill's Dream Chasers label.

Police describe Holden as a convicted violent felon who should be considered armed and dangerous.

Source: http://news.yahoo.com/louisiana-man-36-accused-killing-teen-rapper-025640562.html

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Citrix Systems co-founder dies in Florida

BACO RATON, Fla. (AP) -- Citrix Systems co-founder Edward Iacobucci has died in South Florida. He was 59.

The VirtualWorks Group reports that Iacobucci died at home Friday morning after a 16-month battle with pancreatic cancer.

Iacobucci graduated from Georgia Tech with an engineering degree and got a job working for IBM in 1979. He left IBM in 1989 to co-found Citrix Systems, Inc., where he served chairman and chief technology officer through all of its market and product development phases. He retired in 2000.

In 2002, Iacobucci co-founded DayJet Corporation, which ceased operations in 2008. But a year later, he co-founded VirtualWorks Group, headquartered in Boca Raton, to help customers organize their information. He served as president and CEO there until last month, when he stepped down for health reasons.

Source: http://news.yahoo.com/citrix-systems-co-founder-dies-224918919.html

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Compound enhances SSRI antidepressant's effects in mice

June 21, 2013 ? A synthetic compound is able to turn off "secondary" vacuum cleaners in the brain that take up serotonin, resulting in the "happy" chemical being more plentiful, scientists from the School of Medicine at The University of Texas Health Science Center San Antonio have discovered. Their study, released June 18 by The Journal of Neuroscience, points to novel targets to treat depression.

Serotonin, a neurotransmitter that carries chemical signals, is associated with feelings of wellness. Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed antidepressants that block a specific "vacuum cleaner" for serotonin (the serotonin transporter, or SERT) from taking up serotonin, resulting in more supply of the neurotransmitter in circulation in the extracellular fluid of the brain.

Delicate balance

"Serotonin is released by neurons in the brain," said Lyn Daws, Ph.D., professor of physiology and pharmacology in the School of Medicine. "Too much or too little may be a bad thing. It is thought that having too little serotonin is linked to depression. That's why we think Prozac-type drugs (SSRIs) work, by stopping the serotonin transporter from taking up serotonin from extracellular fluid in the brain."

A problem with SSRIs is that many depressed patients experience modest or no therapeutic benefit. It turns out that, while SSRIs block the activity of the serotonin transporter, they don't block other "vacuum cleaners." "Until now we did not appreciate the presence of backup cleaners for serotonin," Dr. Daws said. "We were not the first to show their presence in the brain, but we were among the first show that they were limiting the ability of the SSRIs to increase serotonin signaling in the brain. The study described in this new paper is the first demonstration of enhancing the antidepressant-like effect of an SSRI by concurrently blocking these backup vacuum cleaners."

Serotonin ceiling

Even if SERT activity is blocked, the backup vacuum cleaners (called organic cation transporters) keep a ceiling on how high the serotonin levels can rise, which likely limits the optimal therapeutic benefit to the patient, Dr. Daws said.

"Right now, the compound we have, decynium-22, is not an agent that we want to give to people in clinical trials," she said. "We are not there yet. Where we are is being able to use this compound to identify new targets in the brain for antidepressant activity and to turn to medicinal chemists to design molecules to block these secondary vacuum cleaners."

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/HE9cAQ04s_w/130621095717.htm

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Saturday, June 22, 2013

Egypt's opposition reaches out to Mubarak's party

CAIRO (AP) ? Egypt's largest opposition grouping is reaching out to members of Hosni Mubarak's ruling party as it gears up for a protest campaign against the current Islamist president.

Members of the ousted autocrat's National Democratic Party have been derided as "feloul" or the "remnants" by both current President Mohammed Morsi and the liberal groups that are his most active opposition. A yet-untested "political isolation" clause in the new constitution may ban senior officials in the now-dissolved party from top posts.

But opposition leader Mohamed ElBaradei told a Cairo conference on Saturday, "I can't isolate millions of Egyptian people because they were part of the National Democratic Party."

ElBaradei made his call in advance of mass protests planned by the opposition for June 30 to demand Morsi's ouster.

Source: http://news.yahoo.com/egypts-opposition-reaches-mubaraks-party-121022114.html

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Report: U.S. charges Snowden, asks Hong Kong to detain him (CNN)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/314409912?client_source=feed&format=rss

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Obama to meet with privacy, civil liberties board

FILE - This Sept. 19, 2007 file photo shows the National Security Agency building at Fort Meade, Md. As many as one of every five worldwide terror threats picked up by U.S. government surveillance has been targeted on the United States, the Obama administration says. But officials are reluctant to say much more about the 50 plots they claim have been thwarted. (AP Photo/Charles Dharapak, File)

FILE - This Sept. 19, 2007 file photo shows the National Security Agency building at Fort Meade, Md. As many as one of every five worldwide terror threats picked up by U.S. government surveillance has been targeted on the United States, the Obama administration says. But officials are reluctant to say much more about the 50 plots they claim have been thwarted. (AP Photo/Charles Dharapak, File)

(AP) ? President Barack Obama is holding his first meeting with a privacy and civil liberties board Friday as he seeks to make good on his pledge to have a public discussion about secretive government surveillance programs.

Obama has said the little-known Privacy and Civil Liberties Oversight Board will play a key role in that effort. The federal oversight board reviews anti-terror programs to ensure that privacy concerns are taken into account.

The president is also tasking the director of national intelligence, James Clapper, to consider declassifying more details about the government's collection of U.S. phone and Internet records. Obama is specifically asking Clapper to review possible declassification of opinions from the Foreign Intelligence Surveillance Court, which approves the surveillance efforts.

Obama's meeting with the board was taking place Friday afternoon, but the White House wasn't planning to allow press coverage.

The government has already lifted some of the secrecy surrounding the programs following disclosures earlier this month about their existence by former National Security Agency contractor Edward Snowden. But the legal opinions from the highly secretive court remain private.

The privacy board was created in 2004 but has operated fitfully ever since, given congressional infighting and at times, censorship by government lawyers. The board was dormant during Obama's first term and only became fully functional in May, before the NSA programs became public.

The board's chairman, David Medine, said the five-member group has a "broad range of questions" to ask about the NSA's widespread collection programs. The board was given a classified briefing on the programs last week and plans to release a report eventually with recommendations for the government.

___

Follow Julie Pace at on Twitter at http://twitter.com/jpaceDC

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-06-21-US-Obama-NSA-Surveillance/id-9687011406bb46d7adce2b216d65a56a

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Friday, June 21, 2013

AP NewsBreak: Report alleges misconduct in BP case

NEW ORLEANS (AP) ? A lawyer working for the court-appointed administrator to review claims as part of the multibillion-dollar settlement over BP's Gulf oil spill has been accused of receiving payments from a law firm representing a claimant, allegations that were discussed in a closed-door meeting Thursday with a federal judge overseeing the case, a BP official with direct knowledge of the situation told The Associated Press.

The BP official, who has reviewed a report outlining the allegations, said claims administrator Patrick Juneau delivered a copy of the report to U.S. District Judge Carl Barbier during a meeting in his chambers. Lawyers for BP and the team of private attorneys who brokered the settlement also attended the meeting. The BP official spoke on condition of anonymity because the report hasn't been made public.

The company official who spoke with the AP did not disclose the name of the individual accused of misconduct but described the person's position and role in the administrator's office.

The report indicates that Juneau's s security head also notified the FBI's New Orleans division about the lawyer's alleged conduct.

An FBI spokeswoman in New Orleans declined to comment Thursday.

The BP official said Juneau told the judge that he has suspended the attorney and is weighing further disciplinary action. Neither Juneau nor his spokesman responded to calls and emails on Thursday night.

The report says the head of security for Juneau's office received a complaint that the staff attorney had referred claims to a New Orleans law firm in exchange for portions of subsequent settlement payments. The lawyer allegedly filed those claims before he went to work for Juneau.

The BP official said the claims at issue were filed on behalf of a single claimant and involve hundreds of thousands of dollars.

BP has sued to block what could be billions of dollars in settlement payouts to businesses over the spill. The London-based oil giant has accused Juneau of trying to rewrite the terms of the deal, claiming he violated the settlement in the way he used a complex formula to determine the payments to businesses.

Barbier appointed Juneau last year and has upheld his decisions for calculating payments. BP has appealed, and the 5th U.S. Circuit Court of Appeals is scheduled to hear the case in July.

The spill began in April 2010 after the BP-leased drilling rig Deepwater Horizon exploded off the Louisiana coast, killing 11 workers. More than 200 million gallons of crude oil were released from the Macondo well a mile under the Gulf surface. Marshes, fisheries and beaches from Louisiana to Florida were fouled by the oil until a cap was placed over the blown-out well in July.

BP was ordered to set up a compensation fund for individuals and businesses affected by the spill and committed $20 billion. The claims fund was handled by lawyer Kenneth Feinberg but it later was transferred to the jurisdiction of U.S. District Court in New Orleans.

Source: http://news.yahoo.com/ap-newsbreak-report-alleges-misconduct-bp-case-032409884.html

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